#117 - Stanley Perlman, M.D., Ph.D.: Insights from a coronavirus expert on COVID-19

Mon, 29 Jun 2020 09:30:00 +0000

In this episode, Stanley Perlman shares insights from his impressive career studying coronaviruses—both the common and more deadly ones, like MERS and SARS. In comparing preceding coronaviruses with SARS-CoV-2, Stanley discusses how other coronaviruses can aid our current understanding of, and be used to infer about, COVID-19. He also gives his thoughts on durable immunity, therapeutic strategies, and future outbreak preparedness.

We discuss:

His background and early work with coronaviruses [2:45];

The coronavirus family—various types, common traits, and scientific understanding [9:00];

The origin of viruses, animal to human transmission, R_0, immunity, and more [17:45];

Insights from the 2002 SARS outbreak [28:30];

Insights from the 2012 MERS outbreak [35:00];

Comparing SARS-CoV-2 to MERS, SARS, and other coronaviruses [42:00];

COVID-19 survivor potential for long-term damage [53:30];

Using the current pandemic for lessons on future preparedness [57:00];

Genetic drift and the potential for long-term immunity to COVID-19 [1:07:00];

Prevention and treatment strategies for COVID-19 and future diseases [1:22:30];

Alternative hypothesis to the origin of SARS-CoV-2 [1:32:30];

Determining durable immunity to COVID-19 and what a successful vaccine looks like [1:34:30]; and

More.

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